Exemestane / Aromasin Powder HPLC :
Exemestane Powder Aromasin Raw Brief Report :
Exemestane Powder (Aromasin) is one of those weird compounds that nobody really knows what to do with. Exemestane’s a third generation Aromatase Inhibitor (AI) just like Arimidex (Anastrozole) and Femera (Letrozole).
Exemestane Powder is one of the most powerful estrogen suppressing compounds available for body builders taking anabolic steroids.Additionally, Exemestane also raises testosterone in the body, which is a bonus for bodybuilders during post-cycle-therapy.Exemestane is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestane is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestane decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
Background
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Exemestane Powder, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.
Summary
Exemestane Powder is an aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
| Product name | Exemestane Powder |
| Alias | Aromasin ; Exemestan; Exemestane(Aromasin); Exemestone |
| CAS No. | 107868-30-4 |
| MF | C20H24O2 |
| MW | 296.4034 |
| Melting point | 155.13℃ |
| Assay | 99%+ |
Applications and uses :
1.Treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause.
2.Adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to exemestane for completion of a total of five consecutive years of adjuvant hormonal therapy.
Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.
Exemestane / Aromasin Powder Effect :
Aromasin is a suicidal aromatase inhibitor (AI), meaning it permanently disables the aromatase enzyme once it binds to it. In plain English, Aromasin will prevent the currently bound enzymes from rebounding, which is what separates this drug from letrozole or arimidex. When you use other AI’s, they temporarily stop estrogen from aromatizing, but when you stop taking them those same enzymes can rebound causing what is known as ‘estrogen rebound’. This explains why some anabolic steroid users experience gynecomastia (bitch tits) after cycle when using other AI’s. Studies on breast cancer patients have shown aromasin reduced estrogen levels up to 85%.
Athletes commonly buy Aromasin to aid in their performance enhancement in conjunction with anabolic steroids. As an aromatase inhibitor Aromasin reduces the amount of estrogen in the body and this is precisely the reason any athlete will buy Aromasin. Make no mistake, Estrogen is essential to our overall well-being but this hormone is also damaging to a physique when levels become too high.When our estrogen levels are too high we will have difficulty in maintaining a lean and hard physique and if were using anabolic steroids a host of negative side-effects can rear their heads.This is why many steroid users buy Aromasin and with proper use they eliminate the potential problems associated with estrogen build up.
Exemestane/Aromasin Powder Dosage ：
This is dependent on the individual and, also, the amount of aromatizing compounds the person is running. Generally, a good starting dose is 12.5mg ED (every day) or 25mg EOD (every other day). The user must utilize blood work to see how their body is reacting at the starting dosage they choose and then adjust as needed. Experienced anabolic steroid users will usually find a dose they like and stick to it with no problems. As I said already, if you start noticing joint issues then the dose should be lowered; on the other hand, if you start noticing any estrogen related sides, such as puffy or sensitive breasts or water retention, it’s time to increase the dosage.
The Benefits of Exemestane / Aromasin Powder：
| Bodybuilding | Steroidal Exemestane inhibitor that act by by decreasing the amount of estrogen produced by the body. It works by limiting the conversion of Testosterone into estrogen and the average rate of estrogen suppression is 85%. The drug also reduces the estradiol levels of about 50%, as well as considerably increases the testosterone levels.
Exemestane inhibitor that works by inhibiting the synthesis of estrogen. Is effective at increasing Testosterone and IGF levels in the body. The drug is also very useful during post cycle therapy regime when one is trying to restore natural Testosterone levels to avoid a post cycle crash. |
| Anti-estrogen drug | Being recognized as one of the most expensive drugs, Exemestane is one of the safest anti-estrogen drugs that is chiefly used by athletes and bodybuilders. Medically the drug is mainly prescribed for the treatment of breast cancer. Commonly referred as Selective Estrogen Receptor Modulator (SERM), it was earlier used for the prevention of gynocomastia. |
Side effects of Exemestane Powder / Aromasin
The most common side effects (more than 10% of patients) are hot flashes and sweating, which are typical of estrogen deficiency as caused by exemestane, and also insomnia, headache, and joint pain. Nausea and fatigue are mainly observed in patients with advanced breast cancer.[6][7]
An occasional decrease in lymphocytes has been observed in approximately 20% of patients receiving Aromasin, particularly in patients with pre-existing lymphopenia.[8]
Exemestane has androgenic properties similarly to formestane and can produce androgenic side effects such as acne and weight gain, although these are generally associated with supratherapeutic dosages of the drug.
Reviews
There are no reviews yet.